Mandevilla manicorensis (Apocynaceae) is here described and illustrated. We also include photo plates, a distribution map, taxonomic comments, and morphological similarities with other species. It is similar to M. rugellosa, but differs by its broader bracts, longer sepals, and orange corolla lobes. A dichotomous key is provided for the species of Mandevilla group “Exothostemon” with hypocrateriform corollas and foliaceous bracts in South America.